Avoid These Common Drugs If You Want to Keep Your Brain Sharp and Prevent Dementia

Absolutely—certain medications can impact cognitive function, especially in older adults, and may increase the risk of memory problems or dementia over time. Here’s a clear guide:

Common Drugs That May Affect Brain Health
Anticholinergics
What they do: Block acetylcholine, a neurotransmitter important for memory and learning.
Examples:
Some antihistamines (diphenhydramine, chlorpheniramine)
Overactive bladder medications (oxybutynin, tolterodine)
Certain antidepressants (tricyclics like amitriptyline)
Brain effect: Linked to memory decline and higher dementia risk with long-term use.
Benzodiazepines